Luxury Boutique Hotels in Italy: A Curated Guide by Region

March 5, 2025

Whether they are luxury hotels, boutique hotels, art & design hotels, these are some of the nicest hotels in Italy. I have organized by region: Rome, Umbria, Tuscany & Florence, Venice, etc. It is a small selection but I will continue to update this post as I vet more hotels. You can browse my Italy posts here. All of the hotels listed below are rated “exceptional”, regardless of price point – a rating given for exceptional hospitality, design and location. I will continue to update the post as I continue on my quest to find the perfect Italy hotels! By clicking on the name of the hotel, you can see photos of the property and rooms.

If you don’t see anything you like here, please contact me and I can help you find the perfect Italian hotel.

Please note that by clicking on some links, at no cost to you, I may make a small commission to help bring you valuable cultural travel content!

Rome

The St. Regis Rome

Number one on my list as it is where I stayed on my honeymoon, the St. Regis Rome just celebrated its 130th anniversary in 2024. The ultimate in elegance and style, the St. Regis in Rome has been the preferred address for royal families, diplomatic delegations, and VIPs. In 2018, the hotel underwent a significant renovation headed up by architect Pierre-Yves Rochon. The hotel offers the ultimate in classic, refined elegance.

Address: Via Vittorio E. Orlando, 3, Rome, Italy (Stazione Termini Area)

Hotel Palazzo Talìa (Spanish Steps – Trevi Fountain)

Ideally located in the center of Rome, this luxury, boutique hotel is a converted 16th-century palazzo. The designer is the film director Luca Guadagnino, who operates his own design studio. Guests will find period architecture and modern design, as only the Italians can do so well. If your budget permits, the top-floor Talìa Suite is the ultimate in Italian luxury, but the other rooms are also well-designed. There is also a spa modeled after a Roman bath. The hotel restaurant, Tramae, serves Italian classics made from farm-fresh ingredients.

Address: Largo del Nazareno 25, Rome, Italy (Spanish Steps – Trevi Fountain)

Chapter Roma

This popular and chic hotel is pure design with rooms in post-industrial and high-gloss, designer furnishings and quirky neon signs. The rooms and interiors are full of delightful gem-toned Art Deco stylishness and a hint of moody modernism. The hotel features a popular rooftop bar and an art filled lobby bar. The restaurant, Campocori, serves a modern take on classic Roman cuisine.

Address: Via S. Maria de’ Calderari 47, Rome, RM, 00186 (Piazza Navona & the Pantheon)

Umbria Region

Vocabolo Moscatelli Boutique Hotel & Restaurant

In the beautiful region of Umbria (2 hours drive south of Florence and approximately 3 hours drive north of Rome), you will find this incredible and very Italian retreat. The style is a blend of 12th century ancient stone walls from what was once a monastery along with very modern and luxurious furnishings. Enjoy the pool, the bar and the restaurant serving Umbrian cuisine with a global twist.

Address: Via del Refari 2, Calzolaro, Umbertide, Italy

Tuscany Region & Florence

Florence_IlDuomo_Exterior_gscinparis — The dome of the Florence Cathedral

Stella d’Italia

Firenze is not short on elegant hotels and yet the Stella d’Italia shines like a star. The location is exceptional as it resides in a 16th-century palazzo designed by Renaissance architect Giorgio Vasari. Just off the beautiful Via Tornabuoni, guests are just a short walk from the Duomo. The design is stunning, the creative masterpiece of a husband and wife duo. Original paintings, eclectic art objects, old film posters and charming antiques from local flea markets make the interior design truly one of a kind.

Some of the rooms include 18th-century frescoes or perhaps an outdoor terrace with a view of the iconic red rooftops. Guests can enjoy the hearty Tuscan breakfast buffet in the frescoed breakfast room or enjoy aperitivi in the cocktail bar in the evening.

Address: Via de Tornabuoni, 7, Florence, Italy (Santa Maria Novella)

Collegio alla Querce

This is Auberge Resorts’ newest European property and is a timeless retreat where high Renaissance art meets modern Italian design surrounded by the tranquil hills of Tuscany. While it is not located in the actual, historic center of Florence, Collegio alla Querce, Auberge Resorts Collection is located in a 16th-century university complex on a secluded hilltop overlooking the city. Guests can view original fresoces and coffered wood ceilings. The guest rooms are the former classrooms and the former headmaster’s office is now the swanky cocktail and cigar lounge. Olive and oak trees surround the pool and there is a spa on the property as well. The Duomo is a 40 minute walk or a 15 minute car ride away.

Address: Via delle Forbici, Florence, Italy

Hotel Lungarno

Stylish and elegant, as only the Florentines can, the Hotel Lungarno sits proudly on the south side of the Arno River with views of the Ponte Vecchio. While there are many dining options in Florence, the hotel has its own wonderful restaurant and classy bar. The Lungarno has an incredible collection of original 20th century works of art, including works by Picasso and Cocteau.

Address: Borgo San Jacopo 14, Florence, Italy (Oltrarno neighborhood)

Monteverdi Tuscany

Castiglioncello del Trinoro is a medieval village on a hilltop in Tuscany’s Val d’Orcia. After WWII, it was basically abandoned. Rome-based architect Ilaria Miani turned a collection of old homes into a luxury boutique hotel. The rooms are charming with wood-beamed cielings, heated floors and classic Italian linens. Some of the suites include views of the vineyards below.

Some of the suites include two to six bedrooms with common areas and a kitchen and a private garden. The hotel is part of the village with ancient cobblestoned streets leading between guest rooms. There is also a pool, lovely gardens, a spa, a library, a terrace bar an art gallery, a cooking school and a 14th century church used for a concert venue.

Address: Via di Mezzo 2, Castiglioncello del Trinoro, Italy

Castiglion del Bosco

For the couple craving a storybook escape. This restored 800-year-old estate is nestled in UNESCO-listed Val d’Orcia, surrounded by rolling vineyards and cypress-lined roads. Perfect for honeymooners, anniversary trips, or anyone wanting to slow down and savor. Think: private villas with countryside views, Brunello wine tastings steps from your door, truffle hunts, and a world-class spa. It’s romance, history, and luxury — all in one.

Address: Localita Castiglion del Bosco, Montalcino, SI, Italy 53024

Borgo Pignano

Ideal for families, creatives, or wellness seekers who want to go off the beaten path. This eco-estate feels like its own enchanted world — 750 acres of wildflower meadows, organic gardens, and olive groves. Stay in a villa or farmhouse, take an art class, explore trails on horseback, or indulge in a Tuscan cooking class. Located near Volterra and San Gimignano, it’s peaceful, inspiring, and totally unique.

Address: Localita Pignano 6, Volterra, PI, Italy 56048

Castello di Casole, A Belmond Hotel

For romantics and aesthetes, this restored castle offers cinematic views, curated experiences, and Belmond’s signature service.

Address: Localita Querceto, 53031 Casole d’Elsa, Italy

Castelfalfi

Ideal for golfers, families, and foodies. This hilltop resort has a championship course, cooking classes, a spa, and panoramic views.

Il Borro Estate

A luxurious countryside escape owned by the Ferragamo family, perfect for wine lovers and design aficionados who want to stay on a working vineyard.

Address: Località Borro, 1, San Giustino Valdarno, Loro Ciuffenna, AR, 52024, Italy

COMO Castello del Nero

Great for wellness seekers and couples — with a world-class spa, Michelin-level dining, and proximity to Florence and Chianti.

Address: Strada Spicciano 7, 50028 Tavarnelle Val di Pesa, Italy

Venice & Veneto Region

Venice, Italy: View of the Grand Canal and the Basilica Santa Maria della Salute

Ca’ Pisani Hotel

Hotel Ca’ Pisani is in a five-hundred-year-old merchant townhouse while the interiors and the restaurant, La Rivista, feature Futurist design. The hotel features a Turkish bath and an incredible rooftop terrace. It is ideally situated in Venice, right next to the Peggy Guggenheim foundation and the Accademia Galleries, and most other significant tourist attractions are within a few minutes’ walk.

Address: Rio Terrà Foscarini, 979/a, Venice, Italy (Dorsoduro area)

Esplanade Tergesteo – Luxury Retreat

Located in a region known even to the Romans for its healing thermal waters, Esplanade Tergesteo is an exceptionally luxurious spa and wellness retreat. With indoor and outdoor pools (including one on the rooftop), a sauna and a Turkish bath, and an impressive array of beauty treatments. Spa suites come with their own saunas, fireplaces and a private deck with a plunge pool. The overall design is sleek yet elegant with views of the surrounding hills.

Address: Via Roma 54, Montegrotto Terme, Italy

Italian Alps & Northern Italy

Grand Hotel Courmayeur Mont Blanc

Grand Hotel Courmayeur Mont Blanc is a sleek and modern 5-star alpine retreat located in the picturesque resort town of Courmayeur, at the foot of Italy’s majestic Mont Blanc. Nestled in the Aosta Valley, the hotel offers easy access to the Courmayeur ski area, including the Dolonne and Plan Checrouit lifts, and is just a short distance from the Skyway Monte Bianco, the panoramic cable car offering breathtaking views of the Alps.

The hotel features elegant, contemporary rooms and suites with large windows, private terraces, and mountain views. Amenities include a full-service spa and wellness center with an indoor pool, sauna, Turkish bath, and treatments designed for post-ski recovery. Guests can also enjoy fine dining at La Fourchette, the hotel’s stylish restaurant serving refined Italian and regional cuisine.

While the hotel itself does not have a Michelin-starred restaurant on-site, it is within a short drive of several Michelin-recognized restaurants in the Aosta Valley region, including:

Bistro Royal at the Grand Hotel Royal e Golf (1 Michelin star), offering elegant tasting menus in nearby Courmayeur.
Café Quinson in Morgex (1 Michelin star), known for its creative reinterpretations of Alpine flavors.

Whether you’re visiting for world-class skiing or a luxurious mountain escape, Grand Hotel Courmayeur Mont Blanc combines Italian sophistication with alpine serenity.

Address: Strada Grand Ru 1, Courmayeur, Italy

Castel Hörtenberg

This Renaissance-era castle is located in Bolzano, in Northern Italy. During the restoration process, centuries of history was revealed and now it offers extremely luxurious lodging. Guests will enjoy sumptuous rooms which retain original elements like timbered ceilings. There is also a spa is more modern in design whereas the old dungeons are now home to Le Segrete, the on-site restaurant.

Address: Via Monte Tondo 4, Bolzano, Italy

Ready to Book Your Trip to Italy?

If Italy is calling sooner, now’s the time — these stunning properties in Italy each offer something unique, and all come with perks you can only access through yours truly! Please see my Book with Me Page for more information.

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What to Wear in Italy!

Ah, my favorite subject! You will want to head to my shop page or my LTK page for curated selections of what to wear to in Europe depending on the season. Plus, save room in your suitcase for all the fabulous shopping you will do while there.